Posted on March 11, 2016

pasteurella multocida ciprofloxacin

Undulant fever Meaning pasteurella multocida ciprofloxacin.

Cephalosporins are bactericidal broad-spectrum antibiotics used to treat skeletal, genital/urinary, skin and soft tissue bacterial and respiratory(associated with Pasteurella sp.) infections, among others. There are several generations of cephalosporin, each aiming a more or less specificgroup of bacteria. Although quite safe when used in injected form, this drug is potentially nephrotoxic. Pasteurella multocida ciprofloxacin.

Due to the ubiquitous nature of P multocida in animals, infection with this organism probably occurs more frequently than is usually appreciated. Ahigh index of suspicion and early diagnosis, especially in immunocompromised patients, are necessary because the disease is potentially lifethreatening (8). The infection is readily treatable and, as demonstrated by sensitivity testing in the case presented, it is susceptible to manyantibiotics. However, P multocida is typically not sensitive to cloxacillin, some first-generation cephalosporins, erythromycin, clindamycin andvancomycin, which are frequently used to treat soft tissue and bone infections. Furthermore, an infection following animal bite or other animalcontact or farm-related injury will initially require a flexible antibiotic approach due to the nonspecific clinical presentation and wide variety ofpossible pathogens. P multocida infections do not have any unique characteristics and may resemble staphylococcal, streptococcal, cat-scratch fever ortularemia infections (9). Although empirical antibiotic therapy may be the initial step, once culture and sensitivity results are available, specifictherapy should be started. Less expensive antibiotic regimens, such as intravenous penicillin or ampicillin followed by oral amoxicillin, may beeffective against P multocida infections provided appropriate antibiotic levels can be attained in the target tissues.

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